Minimal inhibitory concentrations of total 148 strains isolated from blood culture at Seoul National University Hospital were determined by Vitek System.
90% MIC of gram-negative bacteria against amikacin was 2-16㎍/ml, and those against beta-lactams was > 16㎍/ml in general, Except Salmonella spp., 90%MIC against chloramphenicol and tetracycline was >8㎍/ml.
Range of 90%MIC against vancomycin was ≤.5-4㎍/ml in case of gram-positive bacteria, excep tEnterococcus spp. which showed 90%MIC as > 16㎍/ml. Against ampicillin, 90%MIC of Staphylococcus spp. was >16㎍/ml, but those of Streptococcus spp. was≤.25-2㎍/ml. Streptococcus viridans group showed 90%MIC against penicillin as ≤.0.3㎍/ml.
Suceptibility of gram-negative bacteria was generally 985 against amikacin, and those of gram-positive bacteria was 805 against vancomycin. 34% of Staphylococcus spp. was resistant of oxacillin.
These results may be useful for the primary selection and the dosage determination of antibiotics in the treatment of patients with bacteremia.
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